Transcatheter real-time MRI guided myocardial chemoablation using acetic acid
نویسندگان
چکیده
Background In patients with ischemic cardiomyopathy, radiofrequency ablation for ventricular arrhythmias can have limited efficacy because of the mismatch between lesion depth and substrate thickness, and because radiofrequency-induced edema surrounding the lesion is reversible resulting in only temporary conduction block. We hypothesized that transcatheter needle injection under real-time magnetic resonance imaging (MRI) of caustic agents doped with gadolinium contrast could achieve deep targeted and irreversible myocardial ablation which could be assessed acutely.
منابع مشابه
Transcatheter Myocardial Needle Chemoablation During Real-Time Magnetic Resonance Imaging: A New Approach to Ablation Therapy for Rhythm Disorders.
BACKGROUND Radiofrequency ablation for ventricular arrhythmias is limited by inability to visualize tissue destruction, by reversible conduction block resulting from edema surrounding lesions, and by insufficient lesion depth. We hypothesized that transcatheter needle injection of caustic agents doped with gadolinium contrast under real-time magnetic resonance imaging (MRI) could achieve deep, ...
متن کاملTranscatheter Myocardial Needle Chemoablation During Real-Time Magnetic Resonance Imaging
Radiofrequency ablation for rhythm disorders is limited by the inability instantaneously to visualize and monitor ablation lesions and by the mismatch between immediate injury and irreversible conduction block. Magnetic resonance imaging (MRI) thermometry only approximates the extent of irreversible lesions. Late-gadolinium enhancement (LGE) MRI correlates with histological lesion volume but ca...
متن کاملTranscatheter bidirectional Glenn shunt guided by real-time MRI
Methods Ten swine underwent transcatheter bidirectional Glenn procedures under MRI at 1.5T. An MRI antenna-needle was advanced from the superior vena cava (SVC) into the target pulmonary artery (PA) bifurcation using realtime MRI guidance. A caval-pulmonary sheath introduced endografts. Balloon-expansion secured a proximal end-to-end caval anastomosis that also occluded the azygos, and a distal...
متن کاملMagnetic Resonance Imaging-Guided Transcatheter Cavopulmonary Shunt.
OBJECTIVES The aim of this study was to test the hypothesis that real-time magnetic resonance imaging (MRI) would enable closed-chest percutaneous cavopulmonary anastomosis and shunt by facilitating needle guidance along a curvilinear trajectory, around critical structures, and between a superior vena cava "donor" vessel and a pulmonary artery "target." BACKGROUND Children with single-ventric...
متن کاملNeedle-based ablation of renal parenchyma using microwave, cryoablation, impedance- and temperature-based monopolar and bipolar radiofrequency, and liquid and gel chemoablation: laboratory studies and review of the literature.
BACKGROUND AND PURPOSE Small renal tumors are often serendipitously detected during the screening of patients for renal or other disease entities. Rather than perform a radical or partial nephrectomy for these diminutive lesions, several centers have begun to explore a variety of ablative energy sources that could be applied directly via a percutaneously placed needle-like probe. To evaluate th...
متن کامل